AI integration for Sectra Ophthalmology focuses on three primary functional surfaces: the reading worklist, the image viewer, and the reporting module. The goal is to inject AI-derived insights—such as a DR severity score, glaucoma progression probability, or macular edema quantification—at the point of clinical review without disrupting the radiologist's or ophthalmologist's native workflow. This is achieved by connecting to Sectra's DICOM and HL7 APIs to listen for new ophthalmic studies (OCT, fundus photos, visual fields), triggering containerized AI inference services, and writing structured results back as DICOM SR or HL7 ORU messages. These results can then overlay on the viewer, pre-populate report drafts, or prioritize the worklist based on clinical urgency.
Integration
AI Integration for Sectra Ophthalmology

Where AI Fits into the Sectra Ophthalmology Workflow
A practical guide to embedding AI for diabetic retinopathy, glaucoma, and macular edema analysis directly into the Sectra Ophthalmology PACS workflow.
High-value use cases are workflow-specific. For diabetic retinopathy screening, AI can automatically grade fundus images upon ingestion, flagging referable cases (moderate NPDR or worse) for immediate review and routing non-referable cases to a batch queue, turning a manual grading process into a triaged workflow. For glaucoma management, AI models analyzing serial OCT retinal nerve fiber layer (RNFL) maps can quantify progression rates and highlight areas of significant change, presenting a longitudinal analysis directly beside the current study for faster clinical decision-making. For macular edema, AI can segment and quantify fluid volumes on OCT B-scans, providing objective measurements for treatment response tracking that auto-populate into the quantitative section of a structured report.
A production implementation requires careful governance. AI results should be presented as non-interpretive findings—clearly marked as AI-generated suggestions for the clinician to verify. Integration should support a human-in-the-loop review where the radiologist can accept, modify, or reject AI findings, with all actions logged to an audit trail. Rollout typically starts with a pilot in a single clinic or for a single use case (e.g., DR screening), using Sectra's configuration tools to enable the AI overlay for a specific user group before enterprise-wide deployment. This phased approach builds clinician trust and allows for workflow optimization.
For a deeper technical dive on connecting AI models to the broader Sectra platform, see our guide on AI Integration for Sectra PACS. To understand how to architect these cloud-based inference pipelines, review our blueprint for AI Integration for Cloud-Based PACS AI.
Integration Surfaces within Sectra Ophthalmology
OCT and Fundus Photography Workflows
Integrate AI directly into the diagnostic review of Optical Coherence Tomography (OCT) and fundus images. AI models can analyze B-scans and en-face images for quantitative biomarkers, such as retinal layer thickness, drusen volume, and fluid segmentation. These results are embedded as DICOM Structured Reports (SR) or overlays within the Sectra viewer, providing ophthalmologists with automated measurements for conditions like diabetic macular edema, age-related macular degeneration, and glaucoma.
Key integration points include the DICOM Modality Worklist for study ingestion and the Sectra IDS7 DICOM Toolkit for secure data exchange. AI-generated findings can be routed to the Reporting Module to auto-populate structured report templates, standardizing documentation and reducing manual measurement time from minutes to seconds per study.
High-Value AI Use Cases for Ophthalmic Imaging
Integrating AI directly into the Sectra Ophthalmology PACS workflow automates quantitative analysis, prioritizes critical cases, and enriches structured reporting. These use cases connect via DICOM, HL7, and Sectra's APIs to deliver AI insights where clinicians review images and make decisions.
Automated Diabetic Retinopathy Screening
AI analyzes incoming fundus photographs and OCT volumes for referable DR (moderate NPDR or worse, DME). Positive cases are flagged in the Sectra worklist with severity scores and heatmaps overlaid on the viewer. This enables batch screening workflows to be prioritized, reducing manual review time for normal exams.
Glaucoma Progression Analysis
Integrates AI models that compare serial OCT scans and visual field tests over time. The AI calculates rates of RNFL thinning and VF change, generating a progression report that populates a structured template in Sectra Reporting. This provides longitudinal tracking directly within the patient's imaging timeline.
Macular Edema Quantification & Monitoring
For OCT volumes, AI performs automated segmentation of retinal layers and fluid compartments (IRF, SRF). Measurements (central subfield thickness, total fluid volume) are written as DICOM SR and displayed as annotations in the Sectra viewer. Enables objective, repeatable tracking of treatment response.
Critical Finding Triage & Alerting
AI runs on all incoming ophthalmic studies to detect sight-threatening conditions like retinal detachment, vitreous hemorrhage, or advanced glaucoma. Critical cases are escalated to the top of the worklist, and an HL7 alert can be sent to the EHR or a pager system for same-day intervention.
Structured Report Drafting Support
AI-generated findings and measurements are formatted into a pre-populated report draft within the Sectra reporting module. The draft includes quantitative data, AI confidence scores, and relevant prior comparisons. The ophthalmologist edits and finalizes, cutting dictation time and improving report consistency.
Multimodal Study Correlation
AI correlates findings across different imaging modalities (e.g., OCT angiography leaks with OCT fluid, fundus photos with visual fields) for the same patient visit. A unified AI summary is presented in the Sectra viewer, helping clinicians synthesize complex data for comprehensive diagnoses like neovascular AMD.
Example AI-Augmented Clinical Workflows
These workflows illustrate how AI agents and models can be embedded directly into the Sectra Ophthalmology PACS to automate analysis, support decision-making, and streamline documentation. Each workflow is triggered by a study arrival and follows a secure, auditable path through the system.
Trigger: A color fundus photograph study is received by the Sectra VNA for a patient in a diabetic screening program.
Context Pulled: The AI service retrieves the DICOM study and queries the EHR via HL7/FHIR for patient history (HbA1c, last screening date, prior DR grade).
AI Action: A regulatory-cleared DR detection model analyzes the image, generating a structured report (DICOM SR) containing:
- DR severity grade (None, Mild, Moderate, Severe, Proliferative)
- Confidence score
- Image quality assessment
- Location of microaneurysms, hemorrhages, or neovascularization (if present)
System Update: The DICOM SR is sent back to Sectra and linked to the original study. The worklist is automatically updated:
- Studies graded
Moderateor worse are flagged and prioritized to the top of a reading list for an ophthalmologist. - Studies graded
NoneorMildwith high confidence are routed to a "Review & Release" bucket for a quick sign-off by a technician or optometrist.
Human Review Point: All AI findings require final verification and sign-off by a credentialed clinician within the Sectra reporting interface before the report is finalized and sent to the EHR.
Implementation Architecture: Data Flow & APIs
A production-ready architecture for embedding AI directly into the Sectra Ophthalmology workflow, connecting to OCT, fundus, and visual field data.
The integration connects at three primary layers within Sectra Ophthalmology: the DICOM/HL7 ingestion pipeline for incoming studies, the structured reporting module for AI-assisted documentation, and the clinical viewer for AI result overlay. For diabetic retinopathy screening, AI models process incoming color fundus photos via a secure DICOMweb listener. Positive findings trigger an automated HL7 ORU message to flag the study in the worklist and pre-populate the Sectra Reporting template with severity grading (e.g., ICDR levels) and recommended follow-up intervals, saving the ophthalmologist from manual grading and data entry.
For quantitative analysis—such as macular edema thickness from OCT or glaucoma progression from serial visual fields—the architecture uses a containerized inference service deployed within the hospital's secure network. The service pulls anonymized series from the Sectra VNA via its RESTful API, processes them, and returns structured measurements (e.g., central subfield thickness in µm) as DICOM Structured Reports (SR). These SR objects are stored back in the VNA and linked to the original study, making the quantitative data available within the same viewer session without disrupting the clinician's workflow. A key governance element is a human-in-the-loop approval step configured in Sectra's workflow manager, ensuring all AI-generated quantitative data is verified and signed off by the reading physician before finalization.
Rollout follows a phased, use-case-specific approach, starting with non-diagnostic automation like automated image quality control for OCT scans, which reduces technologist recall rates. Subsequent phases introduce diagnostic support tools, each requiring clinical validation, user training, and updates to the Sectra role-based access control (RBAC) system to govern which users can see AI prompts versus final results. The entire pipeline is auditable, with all AI inferences, user interactions, and report modifications logged to Sectra's audit trail for compliance and model performance monitoring. For health systems operating at scale, this architecture supports deployment across a hybrid cloud, with inference services hosted on-premise for PHI-bound data and model training/retraining pipelines operating in a secured cloud environment, synchronized via the Sectra Enterprise Imaging platform's orchestration layer.
Code & Payload Examples
Automating AI Analysis on New Studies
When a new OCT or fundus study is stored in the Sectra VNA, a DICOMweb STOW-RS notification can trigger an AI inference pipeline. This Python example listens for new studies, validates the series description for ophthalmic modalities, and dispatches them to a dedicated AI service for diabetic retinopathy (DR) grading.
pythonimport requests from typing import Dict # Example: Webhook handler for Sectra PACS DICOMweb event def handle_new_ophthalmic_study(study_metadata: Dict): """ Triggered by a DICOMweb STOW-RS notification from Sectra. """ series_desc = study_metadata.get('SeriesDescription', '').lower() # Filter for relevant ophthalmic imaging series ophthalmic_modalities = {'oct', 'fundus', 'color fundus', 'retinal'} if not any(mod in series_desc for mod in ophthalmic_modalities): return {"status": "skipped", "reason": "Non-ophthalmic series"} # Construct payload for AI service ai_payload = { "study_uid": study_metadata['StudyInstanceUID'], "series_uid": study_metadata['SeriesInstanceUID'], "modality": study_metadata['Modality'], "accession_number": study_metadata.get('AccessionNumber'), "ai_workflow": "dr_grading" # Could also be 'glaucoma_progression' or 'dme_quantification' } # Call Inference Systems orchestration endpoint response = requests.post( 'https://api.inferencesystems.com/v1/ophthalmology/analyze', json=ai_payload, headers={'X-API-Key': 'your_key_here'} ) return response.json()
This pattern enables same-day AI analysis on all incoming retinal images, flagging urgent cases for immediate review.
Realistic Time Savings and Operational Impact
How AI integration for Sectra Ophthalmology changes key operational metrics for diabetic retinopathy screening, glaucoma monitoring, and macular edema workflows.
| Workflow / Task | Before AI Integration | After AI Integration | Implementation Notes |
|---|---|---|---|
Diabetic Retinopathy Screening (Fundus Photos) | Manual review of 100+ images per session | AI pre-screens with triage flags; review of 10-20 flagged cases | AI reduces normal case load by ~80%. Human focuses on pathology and borderline cases. |
Glaucoma Progression Analysis (OCT RNFL) | Manual caliper measurements and comparison to prior | AI auto-segments RNFL/GCC, quantifies change, highlights progression zones | Quantification time drops from 5-7 minutes to <1 minute per study. Enables consistent tracking. |
Macular Edema Quantification (OCT) | Manual segmentation of retinal layers and fluid volumes | AI auto-maps intraretinal/subretinal fluid, generates volumetric report | Turns a 3-5 minute manual task into a 30-second verification step. |
Prior Study Comparison for New Patient | Manual retrieval and side-by-side visual comparison | AI auto-registers new to prior scans, overlays change maps, summarizes differences | Comparison time reduced from 4-6 minutes to 1-2 minutes with quantified data. |
Structured Report Drafting | Manual dictation of measurements and findings | AI populates report template with quantified data, leaving findings for clinician edit | Report drafting time cut by 50-70%. Ensures structured data capture for registries. |
Referral Triage & Prioritization | First-in, first-out or manual acuity assessment | AI scores urgency based on detected pathology (e.g., proliferative DR, advanced glaucoma) | Critical cases can be routed to top of worklist, reducing time-to-review for high-risk patients. |
Quality Assurance (Image Gradability) | Technologist or reader manually assesses image quality post-acquisition | AI provides real-time feedback on scan quality (focus, alignment) during acquisition | Reduces recall/re-scan rate; improves downstream AI and human interpretation accuracy. |
Governance, Security, and Phased Rollout
Deploying AI in a regulated ophthalmic workflow requires a controlled, phased approach that prioritizes patient safety, data integrity, and clinician trust.
A production integration for Sectra Ophthalmology must be architected with clinical governance in mind. This typically involves a multi-layered security model where AI inference runs in a secure, HIPAA-compliant container or cloud service, accessing studies via DICOMweb from the Sectra PACS or VNA. All AI-generated observations—such as a DR severity score or macular thickness measurement—are written back as DICOM Structured Reports (SR) or HL7 FHIR observations, creating a permanent, auditable link to the source images within the patient record. Role-based access controls (RBAC) within Sectra ensure only authorized ophthalmologists or technicians can view or act upon AI findings.
We recommend a three-phase rollout to de-risk adoption and build clinical confidence:
- Silent Validation Phase: AI processes historical OCT and fundus images in the background. Results are stored but not displayed in the clinical viewer. This phase builds a performance baseline and validates the AI against your site's patient population and imaging protocols.
- Assistive Notification Phase: AI findings are presented as non-interruptive notifications or secondary findings panels within the Sectra viewer. The ophthalmologist's primary workflow is unchanged, but they can optionally review AI-suggested quantitative data (e.g., edema volume, RNFL thickness maps) to inform their diagnosis.
- Integrated Workflow Phase: AI is fully embedded into key workflows. For example, AI can automatically pre-populate fields in a diabetic retinopathy screening report template or flag studies meeting referral criteria for glaucoma progression, directly within the Sectra worklist. All phases maintain a human-in-the-loop; the AI supports, but does not replace, the clinician's final interpretation.
Change management is critical. Successful implementations establish a clear AI Governance Committee—including lead ophthalmologists, IT, compliance, and clinical engineering—to oversee model validation, monitor for performance drift, and approve progression between rollout phases. This committee also defines protocols for handling AI discrepancies and ensures continuous feedback loops are in place, where clinician corrections can be used to refine local AI performance, all while maintaining strict audit trails for compliance and accreditation.
Enabling Efficiency, Speed & Accuracy
Intelligent Analysis, Decision & Execution
We build AI systems for teams that need search across company data, workflow automation across tools, or AI features inside products and internal software.
Talk to Us
Search across company data
Give teams answers from docs, tickets, runbooks, and product data with sources and permissions.
Useful when people spend too long searching or get different answers from different systems.

Automate internal workflows
Use AI to route work, draft outputs, trigger actions, and keep approvals and logs in place.
Useful when repetitive work moves across multiple tools and teams.

Add AI to products and internal tools
Build assistants, guided actions, or decision support into the software your team or customers already use.
Useful when AI needs to be part of the product, not a separate tool.
FAQ: Technical and Commercial Considerations
Common questions from clinical, IT, and administrative leaders planning AI integration for Sectra Ophthalmology, covering workflow design, technical architecture, and implementation strategy.
Integration typically follows a DICOM-based event-driven pattern, connecting to the Sectra VNA and workflow orchestrator.
Primary Integration Points:
- DICOM Listener/SCP: A secure service listens for incoming studies from modalities (OCT, fundus camera, visual field analyzer) or the PACS archive.
- Study Filtering: Rules (e.g., modality =
OCT, body part =EYE) trigger the AI pipeline, preventing unnecessary processing. - AI Inference Service: Filtered studies are sent to containerized AI models (e.g., for DR grading, macular edema quantification). Results are formatted as DICOM Structured Reports (SR) or HL7 FHIR Observations.
- Result Injection: The AI-generated SR is sent back to the Sectra VNA and linked to the original study. Key findings can also be pushed via HL7 to the EHR for alerting.
- Worklist Prioritization: The Sectra reading worklist can be re-ordered using AI-derived priority scores (e.g.,
Referable DRflagged asSTAT).
Example Payload for AI Trigger:
json{ "study_uid": "1.2.840.113619.2.404.3.2788503.831.1590420507.864", "accession_number": "EYE-2024-12345", "modality": "OCT", "body_part": "RETINA", "patient_id": "P56789", "pre_signed_dicomweb_url": "https://pacs.example.com/studies/1.2.840..." }
This architecture keeps the AI layer decoupled, allowing models to be updated without modifying core Sectra systems.

About the author
Prasad Kumkar
CEO & MD, Inference Systems
Prasad Kumkar is the CEO & MD of Inference Systems and writes about AI systems architecture, LLM infrastructure, model serving, evaluation, and production deployment. Over 5+ years, he has worked across computer vision models, L5 autonomous vehicle systems, and LLM research, with a focus on taking complex AI ideas into real-world engineering systems.
His work and writing cover AI systems, large language models, AI agents, multimodal systems, autonomous systems, inference optimization, RAG, evaluation, and production AI engineering.
Partnered with leading AI, data, and software stack.
How We Work
Custom AI workflows for your Business
One-fit-all AI don't work for modern businesses. At Inferensys, we aim to understand your business & custom requirements; which we use to define most efficient agentic workflows, the data, and the tools for your business.
01
Review the use case
We understand the task, the users, and where AI can actually help.
Read more02
Pick the right approach
We define what needs search, automation, or product integration.
Read more03
Build the first useful version
We implement the part that proves the value first.
Read more04
Improve from there
We add the checks and visibility needed to keep it useful.
Read moreThe first call is a practical review of your use case and the right next step.
Talk to Us