Inferensys

Glossary

GraphQL

An open-source data query and manipulation language for APIs, and a runtime for fulfilling queries with existing data, which allows clients to request exactly the graph-shaped data they need from a single endpoint.
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API QUERY LANGUAGE

What is GraphQL?

GraphQL is an open-source data query and manipulation language for APIs, and a runtime for fulfilling queries with existing data, which allows clients to request exactly the graph-shaped data they need from a single endpoint.

GraphQL is a query language and server-side runtime for APIs that prioritizes giving clients the power to ask for precisely the data they need. Developed internally by Facebook in 2012 and publicly released in 2015, it provides an efficient and powerful alternative to REST by aggregating multiple data requests into a single query, thereby eliminating the common problems of over-fetching and under-fetching data.

The system operates over a single endpoint using a strongly-typed schema to define the capabilities of the API. Clients specify the exact nested fields they require in a hierarchical query, and the server returns a predictable JSON payload mirroring that shape. This declarative model decouples frontend development from backend iteration, enabling rapid feature development without requiring new endpoints.

API ARCHITECTURE

Key Features of GraphQL

GraphQL is a query language and server-side runtime that allows clients to request exactly the data they need from a single endpoint, organized as a graph of connected objects.

01

Declarative Data Fetching

Clients specify the precise shape and fields of the response in the query itself, eliminating over-fetching and under-fetching. The server returns only what is requested, no more and no less. This shifts control from the server to the client, enabling frontend teams to iterate faster without backend changes.

  • Field Selection: Request only patient.name and patient.mrn instead of the entire patient object
  • Nested Resources: Traverse relationships like patient.encounters.diagnosis in a single round trip
  • Aliases: Rename fields in the response to avoid naming conflicts when querying the same field with different arguments
02

Strongly Typed Schema

Every GraphQL API is defined by a strict type system using the Schema Definition Language (SDL). The schema acts as a contract between client and server, specifying object types, fields, relationships, and enumerations. This enables introspection, where tools can automatically query the schema to generate documentation, autocomplete, and validation.

  • Scalar Types: Built-in primitives like String, Int, Float, Boolean, and ID
  • Object Types: Custom types like Patient with fields that resolve to scalars or other objects
  • Enumeration Types: Restrict fields to a predefined set of values, such as Gender: MALE | FEMALE | OTHER
  • Non-Null Modifier: Enforce required fields with String! to guarantee data integrity
03

Single Endpoint Architecture

Unlike REST APIs that require multiple endpoints for different resources, a GraphQL API exposes a single /graphql endpoint. All queries, mutations, and subscriptions are sent to this one URL via HTTP POST. This simplifies client configuration, reduces network overhead, and centralizes authentication, logging, and rate limiting.

  • Query Operation: Read-only data retrieval, analogous to HTTP GET
  • Mutation Operation: Write operations that modify server-side data, analogous to POST/PUT/DELETE
  • Subscription Operation: Real-time event streams over WebSockets for live data updates
  • Batching: Multiple queries can be sent in a single HTTP request as an array
04

Resolver Functions

Each field in a GraphQL schema is backed by a resolver—a function that knows how to fetch the data for that field. Resolvers compose a directed acyclic graph of execution, where parent resolvers pass their resolved values to child resolvers. This enables fetching data from multiple sources like databases, REST APIs, and gRPC services in a single query.

  • Root Resolvers: Entry points for Query, Mutation, and Subscription types
  • Field-Level Resolvers: Granular functions that resolve individual fields, enabling lazy loading
  • DataLoader Pattern: Batching and caching utility to avoid the N+1 query problem when fetching related entities
  • Context Object: Shared mutable object passed through the resolver chain for authentication tokens and database connections
05

Introspection System

GraphQL servers expose a built-in introspection query that allows tools to discover the schema's types, fields, directives, and documentation at runtime. This powers developer tools like GraphiQL and Apollo Studio, which provide interactive API explorers with autocomplete, real-time validation, and schema visualization without requiring external documentation.

  • __schema Query: Returns the full type system including types, queries, mutations, and subscriptions
  • __type Query: Retrieves detailed information about a specific type, including its fields and arguments
  • Deprecation Tracking: Fields can be marked with @deprecated and a reason, surfaced in tooling
  • Schema Stitching: Introspection enables federated gateways to compose multiple subgraphs into a unified supergraph
06

Fragments and Composition

Fragments are reusable units of field selection that reduce duplication in queries. They allow developers to define a set of fields once and spread them into multiple queries, mutations, or other fragments. This is essential for component-based UI frameworks like React, where each component can declare its own data dependencies.

  • Named Fragments: fragment PatientInfo on Patient { name mrn dob } can be reused across queries
  • Inline Fragments: Conditional field selection based on the concrete type in a union or interface
  • Fragment Matching: Tools like Relay enforce colocation of fragments with components for optimal data fetching
  • Type Conditions: Use ... on TypeName to access fields specific to a particular implementation of an interface
API PARADIGM COMPARISON

GraphQL vs. REST vs. SPARQL

A technical comparison of three distinct API paradigms for querying and manipulating data across web services and knowledge graphs.

FeatureGraphQLRESTSPARQL

Data Model

Typed graph schema (SDL)

Resources identified by URIs

RDF triples (subject-predicate-object)

Query Language

Declarative, field-level selection

HTTP methods (GET, POST, PUT, DELETE)

SPARQL query language with graph patterns

Endpoint Architecture

Single endpoint

Multiple resource endpoints

Single SPARQL endpoint

Over-fetching Prevention

Under-fetching Prevention

Response Shape Control

Client-specified exactly

Server-defined fixed structure

Client-specified via SELECT/CONSTRUCT

Standardization Body

GraphQL Foundation (Linux Foundation)

No formal standard (architectural style)

W3C Recommendation

Primary Serialization

JSON

JSON, XML, or any media type

JSON-LD, RDF/XML, Turtle, N-Triples

Schema Introspection

Real-time Subscriptions

Caching Mechanism

Client-side normalized cache required

HTTP caching (ETag, Cache-Control)

Not natively specified

Inference and Reasoning

Federation Support

Apollo Federation, schema stitching

API Gateway composition

SPARQL Federation (SERVICE keyword)

Typical Use Case

Mobile/web apps with complex data needs

CRUD operations, microservices

Knowledge graph querying, linked data

Learning Curve

Moderate

Low

Steep

GRAPHQL IN HEALTHCARE

Frequently Asked Questions

Clear, technical answers to the most common questions about using GraphQL to query and federate clinical knowledge graphs and healthcare data.

GraphQL is an open-source data query and manipulation language for APIs, and a runtime for fulfilling queries with existing data. Unlike REST, which requires multiple round-trips to fixed endpoints to fetch related resources, GraphQL exposes a single endpoint and allows the client to specify exactly the shape and structure of the data it needs in a single request. For clinical data, this means a developer can request a patient's demographics, their latest hemoglobin A1c value, and the prescribing physician's name for a specific medication in one query, traversing the graph of connected medical entities without over-fetching or under-fetching data. This precision is critical for building performant clinical decision support interfaces that require data from disparate FHIR resources and legacy systems.

Prasad Kumkar

About the author

Prasad Kumkar

CEO & MD, Inference Systems

Prasad Kumkar is the CEO & MD of Inference Systems and writes about AI systems architecture, LLM infrastructure, model serving, evaluation, and production deployment. Over 5+ years, he has worked across computer vision models, L5 autonomous vehicle systems, and LLM research, with a focus on taking complex AI ideas into real-world engineering systems.

His work and writing cover AI systems, large language models, AI agents, multimodal systems, autonomous systems, inference optimization, RAG, evaluation, and production AI engineering.